Correlation between wall shear stress and wall rupture properties in ascending thoracic aortic aneurysms

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Biaxial rupture properties of ascending thoracic aortic aneurysms.

UNLABELLED Although hundreds of samples obtained from ascending thoracic aortic aneurysms (ATAA) of patients undergoing elective surgical repair have already been characterized biomechanically, their rupture properties were always derived from uniaxial tensile tests. Due to their bulge shape, ATAAs are stretched biaxially in vivo. In order to understand the biaxial rupture of ATAAs, our group d...

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Wall Shear Stress Analysis in Ascending Aortic Aneurysms using PC VIPR

Introduction Wall shear stress (WSS) has been shown to play a role in aneurysm formation [1] and endothelial cell function [2]. 4D flow techniques using phase contrast (PC) MRI have been used to estimate wall shear stress in a number of vessels, including the ascending aorta [3]. High spatial resolution imaging is important in WSS estimation in order to capture velocity changes at the vessel wa...

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Identification of vessel wall degradation in ascending thoracic aortic aneurysms with OCT.

Degradation of the wall of human ascending thoracic aorta has been assessed through Optical Coherence Tomography (OCT). OCT images of the media layer of the aortic wall exhibit micro-structure degradation in case of diseased aortas from aneurysmal vessels. The OCT indicator of degradation depends on the dimension of areas of the media layer where backscattered reflectivity becomes smaller due t...

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We investigate the flow dynamics and oscillatory behaviour of wall shear stress (WSS) vectors in intracranial aneurysms using high resolution numerical simulations. We analyse three representative patient-specific internal carotid arteries laden with aneurysms of different characteristics: (i) a wide-necked saccular aneurysm, (ii) a narrower-necked saccular aneurysm, and (iii) a case with two a...

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ژورنال

عنوان ژورنال: Computer Methods in Biomechanics and Biomedical Engineering

سال: 2019

ISSN: 1025-5842,1476-8259

DOI: 10.1080/10255842.2020.1713478